Nasal Route

 
Main applications :

The nasal route is conventionally used for :

local treatments : rhinitis (antihistamines and corticosteroids)
   and congestions (decongestants)
systemic administration of pharmaceutical drugs such as hormones,
   or for crisis treatment (migraine, pain)
vaccine administration (i.e. flu vaccine). 		 
 


To enable the administration of medication via the nasal route, Valois offers a wide range of spray devices : nasal multi-dose pumps, unit-dose nasal spray, metering valves with nasal actuator.

 

  

Nasal Multi-dose pumps

Valois offers a wide range of multi-dose nasal spray pumps for liquid formulations (solutions and suspensions), and gels , for both Rx and OTC applications.

Along with these multi-dose systems, Valois also proposes a range of standard and customized accessories complemented by a range of services for the development and the market launch of pharmaceutical drugs for nasal administration :
 

development and customization of drug delivery systems
routine inspection testing
special analytical testing
support for regulatory filing
filling and packaging of pre-clinical and clinical batches.

Unit-dose nasal spray

Unit-dose systems are of single-use type. They have been designed to deliver one or two sprays (one per nostril) of liquid or dry powder formulations or even for extemporaneous mixing of two substances prior to spraying.

Main features :

ready-to-use
easy to use : just push and spray
suitable for ambulatory applications : they can be fired in all positions.


  
   

         Monospray and Dolphin
                                                                          
 These devices enable the administration of 1 or 2 sprays with a dose ranging from 50 to 100 µl.

Main features :

excellent dose accuracy can be sterilized
resistant to bacterial contamination
easy to use
conventional filling system
user-independent performance.
 
   

         Monopowder
                                                                          
 "This active technology" device can deliver doses of dry powder from 20 to 50 mg

Main features :

refillable or disposable system
easy to use
user-independent performance. 
                            

 
   

        Combidose
                                                                          
This device can reconstitute a powder and a liquid or two liquids prior to spraying a 2 x 100 µl dose.

Main features :

can be sterilized
resistant to bacterial contamination
conventional filling system
user-independent performance.

 
   
 
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